Source: | Rabbit | Gene Id: | 5156 |
Isotype: | IgG | Swiss Prot: | P16234 |
purity: | Affinity purification |
Background: |
Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | 140 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:100-1:500
|
Immunogen | A synthetic peptide derived from human PDGFR α |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Alpha platelet-derived growth factor receptor precursor, CD140a, PDGF-R-alpha, PDGFR-alpha, PGFRA, kinase PDGFR-alpha |
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