| No | Size | Price | Availability | |
| ARPF081-61 | 50ul | 1500.00 | In Stock |  |
| ARPF081-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2547/7520 |
| Isotype: | IgG | Swiss Prot: | P12956/P13010 |
| purity: | Affinity purification |
| Background: |
| The Ku autoantigen is a heterodimer of 70kDa (p70) and 80kDa (p80) proteins. The p70 / p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. The Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 70,82 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:100-1:500
|
| Immunogen | A synthetic peptide derived from human Ku70/80 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase II, 80 kDa subunit, CTC box binding factor 85 kDa subunit, CTC85, CTCBF, DNA-repair protein XRCC5, G22P2, KU86, Lupus Ku autoantigen protein p86, Nuclear factor IV, TLAA, Thyroid- lupus autoantigen |
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