| No | Size | Price | Availability | |
| ARP9365P-61 | 50ul | 1500.00 | In Stock |  |
| ARP9365P-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 9365 |
| Isotype: | IgG | Swiss Prot: | Q9UER7 |
| purity: | Affinity purification |
| Background: |
| Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intrinsic E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal degradation. Upon DNA damage, its association with MDM2 and USP7 is disrupted |
| Reactivity | Human, Mouse |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 82 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human Daxx (Phospho-Ser668) |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | BING2, Death domain-associated protein 6, EAP1, ETS1 associated protein 1, Fas DEATH domain- associated protein |
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