Source: | Rabbit | Gene Id: | 9846 |
Isotype: | IgG | Swiss Prot: | Q9UQC2 |
purity: | Affinity purification |
Background: |
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 75 kDa |
Recommended Dilutions |
WB 0.736111
IHC 1:50-1:200
|
Immunogen | A synthetic phosphopeptide derived from human Gab2 around the phosphorylation site of serine 623. |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | GRB2-associated-binding protein 2, Growth factor receptor bound protein 2-associated protein 2, GRB2-associated binder 2, pp100, KIAA0571 |
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