Source: | Rabbit | Gene Id: | 919 |
Isotype: | IgG | Swiss Prot: | P20963 |
purity: | Affinity purification |
Background: |
Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T(-)/B(+)/NK(+) SCID) [MIM:608971]. A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. |
Reactivity | Human, Mouse |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 19 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A synthetic peptide derived from human CD3 ζ (Phospho-Tyr142) |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CD3-zeta, T-cell receptor T3 zeta chain, T-cell surface glycoprotein CD3 zeta chain precursor, T3Z, TCRZ |
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