Source: | Rabbit | Gene Id: | 834 |
Isotype: | IgG | Swiss Prot: | P29466 |
purity: | Affinity purification |
Background: |
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. |
Reactivity | Human, Mouse |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 27 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A synthetic peptide derived from human Caspase 1 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CASP-1, EC 3.4.22.36, ICE, IL-1 beta converting enzyme, IL-1BC, IL1BCE, caspase-1, interleukin-1 beta convertase, interleukin-1 beta converting enzyme, p45 |
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