Source: | Rabbit | Gene Id: | 4322 |
Isotype: | IgG | Swiss Prot: | P45452 |
purity: | Affinity purification |
Background: |
Defects in MMP13 are the cause of spondyloepimetaphyseal dysplasia Missouri type (SEMD-MO) [MIM:602111]. A bone disease characterized by moderate to severe metaphyseal changes, mild epiphyseal involvement, rhizomelic shortening of the lower limbs with bowing of the femora and/or tibiae, coxa vara, genu varum and pear-shaped vertebrae in childhood. Epimetaphyseal changes improve with age. |
Reactivity | Human, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | 54 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:100-1:500
|
Immunogen | A synthetic peptide derived from human MMP 13 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CLG3, matrix metalloproteinase 13 (collagenase 3). |
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