Source: | Rabbit | Gene Id: | 355 |
Isotype: | IgG | Swiss Prot: | P25445 |
purity: | Affinity purification |
Background: |
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. |
Reactivity | Human |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 52 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human FAS |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Apo-1, CD95, FasL receptor, TNFRSF6, TNR6, apoptosis-mediating surface antigen FAS, tumor necrosis factor receptor superfamily member 6 |
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