Source: | Rabbit | Gene Id: | 958 |
Isotype: | IgG | Swiss Prot: | P25942 |
purity: | Affinity purification |
Background: |
Defects in CD40 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3) [MIM:606843]; also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation. |
Reactivity | Human, Mouse |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | 31 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:100-1:500
|
Immunogen | A synthetic peptide derived from human CD40 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | B-cell surface antigen CD40, Bp50, CD40 antigen, CD40L receptor, CDw40, TNR5, tumor necrosis factor receptor superfamily member 5, TNFRSF5 |
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