Source: | Rabbit | Gene Id: | 92283 |
Isotype: | IgG | Swiss Prot: | |
purity: | Purified by Protein A. |
Background: |
GIOT-1 is a 563 amino acid protein belonging to the Kr??ppel C2H2-type zinc-finger protein family. Localized to the nucleus, GIOT-1 is widely expressed in tissues, with highest levels in liver, kidney, small intestine, pancreas and thymus. GIOT-1 contains 12 C2H2-type zinc fincers and one KRAB domain. Because the KRAB domain functions as a transcriptional repressor when attached to the template DNA, GIOT-1 is thought to be involved in transcriptional regulation. The gene encoding GIOT-1 is localized to chromosome 19q13.12 and two isoforms of GIOT-1 exist as a result of alternative splicing events. |
Reactivity | Human |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic peptide derived from human GIOT1/ZNF461 (191-240aa) |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | GIOT-1, GIOT 1, Gonadotropin inducible ovary transcription repressor 1, Gonadotropin inducible transcription repressor 1, Gonadotropin-inducible ovary transcription repressor 1, Zinc finger protein 461, ZN461_HUMAN, ZNF461. |
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