
| Source: | Rabbit | Gene Id: | 4853 |
| Isotype: | IgG | Swiss Prot: | Q04721 |
| purity: | Affinity purification |
| Background: |
| Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 110 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A synthetic peptide derived from human NOTCH2 (Cleaved-Ala1734) |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Neurogenic locus notch homolog protein 2 [Precursor], Notch 2, hN2, Notch 2 extracellular truncation, Notch 2 intracellular domain, NOTCH2 |
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