Source: | Rabbit | Gene Id: | 5315 |
Isotype: | IgG | Swiss Prot: | P14618 |
purity: | Affinity purification |
Background: |
Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 58 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human PKM2 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | PK2 antibodyPK3 antibodyPKM antibodyPKM2 antibodypykm antibodyPyruvate kinase 2/3 antibodyPyruvate kinase 3 antibodyPyruvate kinase isozymes M1/M2 antibodyPyruvate kinase muscle antibodyPyruvate kinase muscle isozyme antibody |
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