RUNX2 Rabbit Polyclonal Antibody
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ARP860-61 50ul 1500.00 In Stock
ARP860-61 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 860
Isotype: IgG Swiss Prot: Q13950
purity: Affinity purification
Background:
Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters (By similarity). Inhibits MYST4-dependent transcriptional activation.
Reactivity Human, Mouse
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW 50-60 kDa
Recommended Dilutions
WB 1:500-1:1000
IHC 1:50-1:200
IF 0.180556
Immunogen A synthetic peptide
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym OSF 2 antibodyOSF-2 antibodyOSF2 antibodyAML3 antibodyCBF alpha 1 antibodyCBF-alpha-1 antibodyCBFA1 antibodyCCD antibodyCCD1 antibody
This product is for research use only, not for diagnostic or therapeutic use!

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