Source: | Rabbit | Gene Id: | 10006 |
Isotype: | IgG | Swiss Prot: | Q8IZP0 |
purity: | Affinity purification |
Background: |
May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 55 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A synthetic peptide derived from human Abi 1 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Abl interactor 1, Abelson interactor 1, Abi-1, Abl-binding protein 4, AblBP4, Eps8 SH3 domain-binding protein, Eps8-binding protein, Nap1-binding protein, Nap1BP, Spectrin SH3 domain-binding protein 1, e3B1, ABI1, SSH3BP1 |
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