Source: | Rabbit | Gene Id: | 2146 |
Isotype: | IgG | Swiss Prot: | Q15910 |
purity: | Affinity purification |
Background: |
Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 85 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human EZH2 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | EZH 2 antibodyEZH1 antibodyEZH2 antibodyEZH2_HUMAN antibodyEZH2b antibodyHistone-lysine N-methyltransferase EZH2 antibodyKMT 6 antibodyKMT6 antibodyKMT6A antibody |
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