
| Source: | Rabbit | Gene Id: | 4092 |
| Isotype: | IgG | Swiss Prot: | O15105 |
| purity: | Affinity purification |
| Background: |
| Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 46 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A synthetic peptide derived from human Smad7 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | SMAD 7 antibodySMAD antibodySMAD family member 7 antibodySMAD, mothers against DPP homolog 7 (Drosophila) antibodySMAD, mothers against DPP homolog 7 antibodySMAD6 antibodySmad7 antibody |
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