Source: | Rabbit | Gene Id: | 4092 |
Isotype: | IgG | Swiss Prot: | O15105 |
purity: | Affinity purification |
Background: |
Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 46 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A synthetic peptide derived from human Smad7 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | SMAD 7 antibodySMAD antibodySMAD family member 7 antibodySMAD, mothers against DPP homolog 7 (Drosophila) antibodySMAD, mothers against DPP homolog 7 antibodySMAD6 antibodySmad7 antibody |
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