| No | Size | Price | Availability | |
| ARP5295-62 | 50ul | 1500.00 | In Stock |  |
| ARP5295-62 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5295 |
| Isotype: | IgG | Swiss Prot: | P27986 |
| purity: | Affinity purification |
| Background: |
| Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 83 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human PI3 kinase P85α |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | GRB1, P85A, phosphatidylinositol 3-kinase regulatory alpha subunit, PI3-kinase p85-alpha, PI3K, PI3K p85-alpha, ptdIns-3-kinase p85-alpha |
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