Source: | Rabbit | Gene Id: | 967 |
Isotype: | IgG | Swiss Prot: | P08962 |
purity: | Affinity purification |
Background: |
Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGF |
Reactivity | Human |
Tested applications | IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 25 kDa |
Recommended Dilutions |
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human CD63 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CD63 antigen, Melanoma-associated antigen ME491, Ocular melanoma-associated antigen, OMA81H, Granulophysin, Tetraspanin-30, Tspan-30, Lysosomal-associated membrane protein 3, Lamp-3, CD63, MLA1, TSPAN30 |
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