Source: | Rabbit | Gene Id: | 7248 |
Isotype: | IgG | Swiss Prot: | Q92574 |
purity: | Affinity purification |
Background: |
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 150-170 kDa |
Recommended Dilutions |
WB 0.736111
IHC 1:50-1:200
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Hamartin antibodykiaa0243 antibodyLAM antibodyTSC antibodyTSC1 antibodyTsc1 gene antibody |
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