| No | Size | Price | Availability | |
| ARP6597-61 | 50ul | 1500.00 | In Stock |  |
| ARP6597-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6597 |
| Isotype: | IgG | Swiss Prot: | P51532 |
| purity: | Affinity purification |
| Background: |
| Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 185,200 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | Peptide sequence around aa.701~705(V-D-A-R-H) derived from Human Brg1. |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | BRG1, SNF2, SWI2, RTPS2, BAF190 |
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