| No | Size | Price | Availability | |
| ARP1869-62 | 50ul | 1500.00 | In Stock |  |
| ARP1869-62 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 1869 |
| Isotype: | IgG | Swiss Prot: | Q01094 |
| purity: | Affinity purification |
| Background: |
| Transcription activator that binds DNA cooperatively with dp proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-1 binds preferentially RB1 protein, in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent apoptosis. "P53 and E2F-1 cooperate to mediate apoptosis." |
| Reactivity | Human, Mouse |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 70 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | Peptide sequence around aa.430~434(G-D-L-T-P) derived from Human E2F-1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | RBP3, E2F-1, RBAP1, RBBP3 |
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