| No | Size | Price | Availability | |
| ARP6015-61 | 50ul | 1500.00 | In Stock |  |
| ARP6015-61 | 100ul | 2000.00 | In Stock | |
| Source: | Gene Id: | 6015 | |
| Isotype: | IgG | Swiss Prot: | Q06587 |
| purity: | Affinity purification |
| Background: |
| Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 58 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | Peptide sequence around aa.35~39( I-A-V-S-P) derived from Human Ring1A. |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | RNF1, RING1 |
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