| No | Size | Price | Availability | |
| ARP5315-64 | 50ul | 1500.00 | In Stock |  |
| ARP5315-64 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5315 |
| Isotype: | IgG | Swiss Prot: | P14618-1 |
| purity: | Affinity purification |
| Background: |
| Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 60 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | Peptide sequence around aa.405~409(T-S-D-P-T) derived from Human PKM2. |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | PKM, PK3, OIP3, PK2 |
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