Nanog Rabbit Polyclonal Antibody
No Size Price Availability  
ARP79923-61 50ul 1500.00 In Stock
ARP79923-61 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 79923
Isotype: IgG Swiss Prot: Q9H9S0
purity: Affinity purification
Background:
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes By similarity. Acts as a transcriptional activator or repressor By similarity. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' By similarity. When overexpressed, promotes cells to enter into S phase and proliferation
Reactivity Human, Mouse
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 42 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen Peptide sequence around aa.137~141 (K-Q-V-K-T) derived from Nano g
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym Homeobox transcription factor Nanog
This product is for research use only, not for diagnostic or therapeutic use!

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