TORC2 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP200186-61 50ul 1500.00 In Stock
ARP200186-61 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 200186
Isotype: IgG Swiss Prot: Q53ET0
purity: Affinity purification
Background:
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
Reactivity Human, Mouse, Rat
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 70 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen peptide from human TORC2
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym
This product is for research use only, not for diagnostic or therapeutic use!

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