Source: | Rabbit | Gene Id: | 6794 |
Isotype: | IgG | Swiss Prot: | Q15831 |
purity: | Affinity purification |
Background: |
ubiquitously expressed kinase of the CAMKL family with a tumor suppressor activity. Phosphorylates AGS3 (activator of G-protein signaling 3) GPR domains, regulating the interaction of GPR-containing proteins with G-proteins. Strongest expression in testis and fetal liver. Mutations in LKB1 lead to the Peutz-Jeghers cancer syndrome. |
Reactivity | Human, Mouse |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 65 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A synthetic peptide derived from human LKB1 around the phosphorylation site of Threonine 189 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Protein kinase, Ser/Thr (non-receptor), CAMK group, CAMKL family, LKB subfamily |
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