| No | Size | Price | Availability | |
| YRP11373-01 | 50ul | 1500.00 | In Stock |  |
| YRP11373-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 60412 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| Exocytosis is crucial in membrane trafficking and it mediates hormone and neurotransmitter secretion out of the cell, as well as the incorporation of membrane proteins and lipids to the plasma membrane. It is crucial for cell-cell communication, cell growth and cell polarity. The exocyst complex is a multi-protein complex that consists of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84, and is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. The exocyst complex inhibits tubulin polymerization in vitro, suggesting that the exocyst complex is important for modulating the microtubule dynamics that underlie exocytosis. Sec8, also known as EXOC4 (exocyst complex component 4), REC8 or SEC8L1, is one of eight protein subunits composing the mammalian exocyst complex. Human Sec8 maps to chromosome 7q33. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human Sec8 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | dSec8, EXOC 4, Exoc4, EXOC4_HUMAN, Exocyst complex component 4, Exocyst complex component Sec8, KIAA1699, MGC27170, REC 8, REC8, rSec 8, Sec 8, Sec 8p, Sec8, SEC8 like 1, SEC8 protein, Sec8L1, Sec8p. |
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