| No | Size | Price | Availability | |
| ARP2308P-62 | 50ul | 1500.00 | In Stock |  |
| ARP2308P-62 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2308 |
| Isotype: | IgG | Swiss Prot: | Q12778 |
| purity: | Affinity purification |
| Background: |
| This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. Interacts with LRPPRC. Interacts with RUNX2; the interaction inhibits RUNX2 transcriptional activity and mediates the IGF1/insulin-dependent BGLAP expression in osteoblasts Interacts with PPP2R1A; the interaction regulates the dephosphorylation of FOXO1 at Thr-24 and Ser-256 leading to its nuclear import. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 69 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human FOXO1 around the phosphorylation site of Ser256 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | FKH1, FKHR, FOXO1A |
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