
| Source: | Rabbit | Gene Id: | 1234 |
| Isotype: | IgG | Swiss Prot: | P51681 |
| purity: | Affinity purification |
| Background: |
| CCR5 a 7-transmembrane G-linked receptor for a number of inflammatory C-C type chemokines including MIP-1-alpha, MIP-1-beta and RANTES. Transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (along with CD4) for HIV-1 R5 isolates. Interacts with PRAF2. Interacts with HIV-1 surface protein gp120. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 40 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A synthetic peptide derived from human CCR5 around the phosphorylation site of Serine 336 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Protein name C-C chemokine receptor type 5 ,Synonyms C-C CKR-5,CC-CKR-5,CCR-5,CCR5,HIV-1 fusion coreceptor,CHEMR13,CD195 antigen, Gene name Name: CCR5, Synonyms: CMKBR5 |
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