Source: | Rabbit | Gene Id: | 2931 |
Isotype: | IgG | Swiss Prot: | P49840 |
purity: | Affinity purification |
Background: |
GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IP |
Clonality | Polyclonal Antibody |
Calculated MW | 51 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human GSK3 alpha around the phosphorylation site of Serine 21 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | DKFZp686D0638, glycogen synthase kinase 3 alpha, Glycogen synthase kinase-3 alpha, GSK-3 alpha, GSK3A |
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