Source: | Rabbit | Gene Id: | 5829 |
Isotype: | IgG | Swiss Prot: | P49023 |
purity: | Affinity purification |
Background: |
PXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 68 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A synthetic peptide derived from human Paxillin around the phosphorylation site of Tyrosine 118 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Paired box protein Pax-1, PAX-1, PAXI, paxillin, paxillin alpha |
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