| No | Size | Price | Availability | |
| ARP1027P-61 | 50ul | 1500.00 | In Stock |  |
| ARP1027P-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 1027 |
| Isotype: | IgG | Swiss Prot: | P46527 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 27 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A synthetic peptide derived from human p27 Kip1 around the phosphorylation site of Threonine 198 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CDKN4, KIP1, MEN1B, MEN4, P27KIP1 |
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