
| Source: | Rabbit | Gene Id: | 836 |
| Isotype: | IgG | Swiss Prot: | P42574 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 34 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human Caspase 3 around the phosphorylation site of Serine 150 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Apopain precursor, CASP-3, CPP-32, CPP32, Caspase-3, Cysteine protease CPP32, EC 3.4.22.-, ICE3, SCA-1, SREBP cleavage activity 1, Yama protein |
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