Source: | Rabbit | Gene Id: | 672 |
Isotype: | IgG | Swiss Prot: | P38398 |
purity: | Affinity purification |
Background: |
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as BASC for BRCA1-associated genome surveillance complex. |
Reactivity | Human, Rat |
Tested applications | IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 220 kDa |
Recommended Dilutions |
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human BRCA1 around the phosphorylation site of Serine 1423 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | BRCA1, Breast cancer type 1 susceptibility protein, familial breast/ovarian cancer gene 1 |
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