
| Source: | Rabbit | Gene Id: | 672 |
| Isotype: | IgG | Swiss Prot: | P38398 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as BASC for BRCA1-associated genome surveillance complex. |
| Reactivity | Human, Rat |
| Tested applications | IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 220 kDa |
| Recommended Dilutions |
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human BRCA1 around the phosphorylation site of Serine 1423 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | BRCA1, Breast cancer type 1 susceptibility protein, familial breast/ovarian cancer gene 1 |
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