Source: | Rabbit | Gene Id: | 3667 |
Isotype: | IgG | Swiss Prot: | P35568 |
purity: | Affinity purification |
Background: |
IRS-1 is an adaptor protein that is one of the major substrates of the insulin receptor kinase. Contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain-containing proteins including phosphatidylinositol 3-kinase p85 subunit and GRB-2. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 180 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide derived from human IRS-1 around the phosphorylation site of Serine 312 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | IRS-1, IRS1, Insulin receptor substrate-1 |
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