Source: | Rabbit | Gene Id: | 5610 |
Isotype: | IgG | Swiss Prot: | P19525 |
purity: | Affinity purification |
Background: |
PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis. |
Reactivity | Human |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 74 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A synthetic peptide derived from human PKR around the phosphorylation site of Threonine 446 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | EC 2.7.11.1Interferon-inducible RNA-dependent protein kinaseEukaryotic translation initiation factor 2-alpha kinase 2eIF-2A protein kinase 2Protein kinase RNA-activatedPKRp68 kinaseP1/eIF-2A protein kinase |
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