| No | Size | Price | Availability | |
| ARP4914P-61 | 50ul | 1500.00 | In Stock |  |
| ARP4914P-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 4914 |
| Isotype: | IgG | Swiss Prot: | P04629 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 87 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A synthetic peptide derived from human Trk A around the phosphorylation site of Tyrosine 680+Tyrosine 681 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | EC 2.7.10.1, High affinity nerve growth factor receptor precursor, NTRK1, Slow nerve growth factor receptor, TRK, TRK1 transforming tyrosine kinase protein, TRKA, Trk-A, kinase TrkA, p140-TrkAMolecular weight: 87511.17 |
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