
| Source: | Rabbit | Gene Id: | 25/27 |
| Isotype: | IgG | Swiss Prot: | P00519/P42684 |
| purity: | Affinity purification |
| Background: |
| The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. |
| Reactivity | Human, Mouse |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 135 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human Abl around the phosphorylation site of Tyrosine 412 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | EC 2.7.10.2p150c-ABLAbelson murine leukemia viral oncogene homolog 1/EC 2.7.10.2Abelson murine leukemia viral oncogene homolog 2Abelson-related gene proteinTyrosine kinase ARG |
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