Source: | Rabbit | Gene Id: | 1147 |
Isotype: | IgG | Swiss Prot: | O15111 |
purity: | Affinity purification |
Background: |
IKK-alpha a kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B, leading to their dissociation from NF-kappa-B and ultimately to their degradation. Phosphorylated and activated downstream of growth factor receptors, IL1R, and TNFR by NAK, IRAK and NIK, respectively. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 85 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human IKK- alpha around the phosphorylation site of Threonine 23 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CHUK, conserved helix-loop ubiquitous kinase, Conserved helix-loop-helix ubiquitous kinase, I-kappa-B kinase 1, I-kappa-B kinase alpha, I-kappa-B kinase-alpha, IkappaB kinase, IkB kinase alpha subunit, IkBKA, IKK-A, IKK-a kinase, IKK-alpha, IKK1, IKKA |
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