Source: | Rabbit | Gene Id: | 4792 |
Isotype: | IgG | Swiss Prot: | P25963 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 39 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide derived from human NFKBIA around the phosphorylation site of Serine 32/Serine 36 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | IKBA, MAD-3, NFKBI |
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