| No | Size | Price | Availability | |
| ARP8350A-62 | 50ul | 1500.00 | In Stock |  |
| ARP8350A-62 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 3020/126961/3021 |
| Isotype: | IgG | Swiss Prot: | P68431/Q71DI3/P84243 |
| purity: | Affinity purification |
| Background: |
| H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 15 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 0.180556
|
| Immunogen | A synthetic peptide derived from human Histone H3 around the acetylated site of Lys18. |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | H3 histone antibody, HIST1H3A antibody, Histone cluster 1, H3a antibody |
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