| No | Size | Price | Availability | |
| ARPF009P-62 | 50ul | 1500.00 | In Stock |  |
| ARPF009P-62 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5594/5595 |
| Isotype: | IgG | Swiss Prot: | P27361/P28482 |
| purity: | Affinity purification |
| Background: |
| Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 42,44 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human ERK1/2 around the phosphorylation site of Threonine 202/Tyrosine 204 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | ERK-1, ERK1, ERT2, Extracellular signal- regulated kinase 1, Insulin-stimulated MAP2 kinase, kinase ERK1, MAP kinase 1, MAPK 1, MAPK3, Microtubule- associated protein-2 kinase, Mitogen-activated protein kinase 3, MK03, MNK1, p44-ERK1, P44-ERK1, p44-MAPK |
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