Source: | Rabbit | Gene Id: | 8349/8970 |
Isotype: | IgG | Swiss Prot: | P62807/P06899/Q16778/P57053 |
purity: | Affinity purification |
Background: |
H2BFS a core component of the nucleoosome. The nucleosome, a basic organizational unit of chromosomal DNA, is octrameric, consisting of two molecules each of histones H2B, H2A, H3, H4. The octamer wraps approximately 147 bp of DNA. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. |
Reactivity | Human, Mouse |
Tested applications | IHC IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 14 kDa |
Recommended Dilutions |
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide derived from human Histone H2B |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | H2B histone family, member S, H2B/s, H2BFS, Histone H2B type F-S, Histone H2B.s |
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