Source: | Rabbit | Gene Id: | 132243 |
Isotype: | IgG | Swiss Prot: | Q8IZA3 |
purity: | Affinity purification |
Background: |
H1FOO May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling. |
Reactivity | Human |
Tested applications | WB IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 21 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide derived from human Histone H1 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | H1 histone family, member O, oocyte-specific, H1FOO, H1OO, Histone H1oo, MGC50807, Oocyte-specific histone H1, Oocyte-specific linker histone H1, OSH1 |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.