Source: | Rabbit | Gene Id: | 8550 |
Isotype: | IgG | Swiss Prot: | Q8IW41 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Reactivity | Human, Mouse |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 60 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A synthetic peptide derived from human MAPKAPK5 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | EC 2.7.11.1, MAP kinase-activated protein kinase 5, MAPK-activated protein kinase 5, MAPK5, MAPKAP kinase 5, p38-regulated/activated protein kinase, PRAK |
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