Source: | Rabbit | Gene Id: | 4683 |
Isotype: | IgG | Swiss Prot: | O60934 |
purity: | Affinity purification |
Background: |
NBS1 is a member of the MRE11/RAD50 double-strand break repair complex. Involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. Mutation results in the Nijmegen breakage syndrome (NBS), an autosomal recessive chromosomal instability syndrome. |
Reactivity | Human |
Tested applications | WB IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 85 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide derived from human Nibrin |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Cell cycle regulatory protein P95, NBN, NBS, NIBRIN, NIJMEGEN BREAKAGE syndrome protein 1, p95-NBS1 |
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