
| Source: | Rabbit | Gene Id: | 2191 |
| Isotype: | IgG | Swiss Prot: | Q12884 |
| purity: | Affinity purification |
| Background: |
| PTPN13 Tyrosine phosphatase which regulates negatively FAS- induced apoptosis and NGFR-mediated pro-apoptotic signaling. Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. Interacts with TRIP6 and TNFRSF6 (Fas receptor) through its second PDZ domain. Interacts with the C-terminal SVP motif of NGFR through its third PDZ domain. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 88 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human FAP-1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | APO-1/CD95 (Fas)-associated phosphatase, DKFZp686J1497, FAP-1, Fas-associated phosphatase-1, Fas-associated protein-tyrosine phosphatase 1, hPTPE1, PNP1, protein tyrosine phosphatase 1E, protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas |
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