GRP78 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP3309-61 50ul 1500.00 In Stock
ARP3309-61 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 3309
Isotype: IgG Swiss Prot: P11021
purity: Affinity purification
Background:
GRP78 a member of the HSP family of molecular chaperones required for endoplasmic reticulum integrity and stress-induced autophagy. Plays a central role in regulating the unfolded protein response (UPR), and is an obligatory component of autophagy in mammalian cells.. May play an important role in cellular adaptation and oncogenic survival. One of the client proteins of GRP78 is protein double-stranded RNA-activated protein-like endoplasmic reticulum kinase (PERK).
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF ICC
Clonality Polyclonal Antibody
Calculated MW 75 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
Immunogen A synthetic peptide derived from human GRP78
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym 78 kDa glucose-regulated protein, BiP, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, FLJ26106, GRP-78, GRP78, Heat shock 70 kDa protein 5, heat shock 70kD protein 5 (glucose-regulated protein, 78kD), heat shock 70kDa protein 5 (glucose-regul
This product is for research use only, not for diagnostic or therapeutic use!

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