| No | Size | Price | Availability | |
| ARP55240-61 | 50ul | 1500.00 | In Stock |  |
| ARP55240-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 55240 |
| Isotype: | IgG | Swiss Prot: | Q658P3 |
| purity: | Affinity purification |
| Background: |
| STEAP3 a multi-pass membrane protein induced directly by p53. Plays an important role in facilitating exosome secretion. Enhances secretion in the DNA damage-induced p53-dependent exosomal secretory pathway. Localizes to vesicular-like structures at the plasma membrane and around the nucleus. Highly expressed in hematopoietic tissues where it localizes to the specialized endosome. An endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NAD(+) as acceptor. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 54 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IF 1:100-1:500
ICC 1:100-1:500
|
| Immunogen | A synthetic peptide derived from human STEA3 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | 1010001D01Rik, dudlin 2, dudlin-2, dudulin 2, Dudulin-2, hpHyde, hTSAP6, Metalloreductase STEAP3, pHyde, six transmembrane prostate protein 3, Six-transmembrane epithelial antigen of prostate 3, STEA3, STEAP family member 3, STEAP3, STMP3, TSAP6, tumor su |
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