Source: | Rabbit | Gene Id: | 54908 |
Isotype: | IgG | Swiss Prot: | Q96EA4 |
purity: | Affinity purification |
Background: |
CCDC99 Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. |
Reactivity | Human |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 70 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A synthetic peptide derived from human CCDC99 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Arsenite-related gene 1 protein, CCDC99, coiled-coil domain containing 99, Coiled-coil domain-containing protein 99, FLJ20364, FLJ40690, hSpindly, Rhabdomyosarcoma antigen MU-RMS-40.4A, rrhabdomyosarcoma antigen protein MU-RMS-40.4A, SPDLY, Spindly |
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